The Rho kinase 2 (ROCK2)-specific inhibitor KD025 ameliorates the development of pulmonary arterial hypertension
Aya Yamamura, Md Junayed Nayeem, Motohiko Sato
Topics & Concepts
ROCK2ROCK1Pulmonary hypertensionPulmonary arteryMedicineFasudilPathogenesisIn vivoKinasePharmacologyRho-associated protein kinaseGene isoformInternal medicineCardiologyChemistryBiologyProtein kinase ABiochemistryGeneBiotechnologyPulmonary Hypertension Research and TreatmentsProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer