Netrin-like domain of sFRP4, a Wnt antagonist inhibits stemness, metastatic and invasive properties by specifically blocking MMP-2 in cancer stem cells from human glioma cell line U87MG
Ishmat Ara Yasmin, Sumati Sundaram, Anasuya Banerjee, Lavanya Varier, Arun Dharmarajan, Sudha Warrier
Topics & Concepts
BiologyGliomaCancer researchMetastasisCancer stem cellMatrigelWnt signaling pathwayMatrix metalloproteinaseCell cultureCell biologyStem cellCancerSignal transductionAngiogenesisBiochemistryGeneticsAxon Guidance and Neuronal SignalingHedgehog Signaling Pathway StudiesWnt/β-catenin signaling in development and cancer