Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes
Perihan A. Elzahhar, Rebecca Orioli, Nayera W. Hassan, Silvia Gobbi, Federica Belluti, Hala F. Labib, Ahmed F. El‐Yazbi, Rasha A. Nassra, Ahmed S.F. Belal, Alessandra Bisi
Topics & Concepts
ChemistryChromoneEnzymePharmacologyIn silicoDocking (animal)BiochemistryStereochemistryGeneNursingMedicineSynthesis and biological activityInflammatory mediators and NSAID effectsBioactive Compounds and Antitumor Agents