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Design, Synthesis and Biological Evaluation of Phenoxyacetic Acid derivatives Linked to Pyrazole Scaffold as PPAR-α/γ Agonists and COX-2 Inhibitors with Dual Antidiabetic/Anti-inflammatory Activities

Wael A. A. Fadaly, Dina M. E. Amin, Rania B. Bakr, Mohamed T. M. Nemr, Basma S. Ismail, Mamdouh F. A. Mohamed

2025Journal of Molecular Structure16 citationsDOI

Topics & Concepts

ChemistryPyrazoleScaffoldAnti-inflammatoryPeroxisome proliferator-activated receptorCombinatorial chemistryPharmacologyStereochemistryBiochemistryReceptorMedicineBiomedical engineeringPeroxisome Proliferator-Activated ReceptorsEicosanoids and Hypertension PharmacologyInflammatory mediators and NSAID effects
Design, Synthesis and Biological Evaluation of Phenoxyacetic Acid derivatives Linked to Pyrazole Scaffold as PPAR-α/γ Agonists and COX-2 Inhibitors with Dual Antidiabetic/Anti-inflammatory Activities | Litcius