Silencing EIF3A ameliorates pulmonary arterial hypertension through HDAC1 and PTEN/PI3K/AKT pathway in vitro and in vivo
Haitao Yang, Guan Wang, Pengcheng Zhu, Zhaoyang Xiao
Topics & Concepts
PTENBiologyPI3K/AKT/mTOR pathwayProtein kinase BCancer researchGene silencingGene knockdownSmall hairpin RNASignal transductionCell biologyCell cultureGeneticsGeneBiochemistryPulmonary Hypertension Research and TreatmentsPI3K/AKT/mTOR signaling in cancerCancer-related gene regulation