Crosslinked ionizable lipids reprogram dendritic cell metabolism for potent mRNA vaccination
Dongyoon Kim, Ningqiang Gong, Mohamad-Gabriel Alameh, Emily L. Han, Hanxun Wang, Jinjin Wang, Ellie Feng, Ilchul Yoon, Amanda M. Murray, Qiangqiang Shi, So-Jeong Moon, Kaitlin Mrksich, Drew Weissman, Michael J. Mitchell
Topics & Concepts
Dendritic cellChemistryMessenger RNAMetabolismCell biologyVaccinationLipid metabolismCellBiochemistryImmune systemBiologyGene expressionCell cultureCell metabolismImmunotherapyMolecular biologyLiposomeRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesDendrimers and Hyperbranched Polymers