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Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut

Yiqing Yan, Deepshika Ramanan, Milena Rozenberg, Kelly McGovern, Daniella Rastelli, Brinda Vijaykumar, Omar Yaghi, Tiphaine Voisin, Munir M. Mosaheb, Isaac M. Chiu, Shalev Itzkovitz, Meenakshi Rao, Diane Mathis, Christophe Benoıst

2021Immunity150 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEnteric nervous systemFOXP3Cell biologyLamina propriaImmune systemRAR-related orphan receptor gammaImmunologyNeuronRegulatory T cellT cellNeuroscienceEpitheliumIL-2 receptorGeneticsGastrointestinal motility and disordersImmune Cell Function and InteractionHelicobacter pylori-related gastroenterology studies
Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut | Litcius