Engineering ultrasound-activated piezoelectric hydrogels with antibacterial activity to promote wound healing
Min Xu, Shaozhen Wu, Li Ding, Caijiao Lu, Huangjing Qian, Jinmiao Qu, Yu Chen
Abstract
results have demonstrated that piezoelectric hydrogels can accelerate full-thickness skin wound healing in bacteria-infected mice by skin regeneration, inhibiting inflammatory response, increasing collagen deposition, and promoting angiogenesis. Such a discovery provides a representative paradigm for the rational design of piezoelectric hydrogel and effectively serves antibacterial and wound dressing fields.
Topics & Concepts
Materials scienceWound healingSelf-healing hydrogelsChitosanRegeneration (biology)In vivoPiezoelectricityTannic acidAngiogenesisBiomedical engineeringTissue engineeringAdhesionAdhesiveAntibacterial activityNanotechnologyComposite materialChemistrySurgeryBacteriaMedicineCell biologyPolymer chemistryCancer researchBiochemistryOrganic chemistryGeneticsBiotechnologyBiologyLayer (electronics)Wound Healing and TreatmentsPlanarian Biology and ElectrostimulationPressure Ulcer Prevention and Management