Controlling Inflammation Improves Aging Skeletal Muscle Health
William A. Fountain, Masatoshi Naruse, Alex Claiborne, Scott Trappe, Todd A. Trappe
Abstract
Chronic inflammation is associated with a decline in aging skeletal muscle health. Inflammation also seems to interfere with the beneficial skeletal muscle adaptations conferred by exercise training in older individuals. We hypothesize that the cyclooxygenase pathway is partially responsible for this negative inflammatory influence on aging skeletal muscle health and plasticity.
Topics & Concepts
Skeletal muscleInflammationMedicineEndocrinologyInternal medicineExercise and Physiological ResponsesAdipokines, Inflammation, and Metabolic DiseasesFibromyalgia and Chronic Fatigue Syndrome Research