Design, synthesis and biological evaluation of novel 1,2,3-triazole-based xanthine derivatives as DPP-4 inhibitors
Sirassu Narsimha, Kumara Swamy Battula, M. Ravinder, Y. N. Reddy, Vasudeva Reddy Nagavelli
Topics & Concepts
Dipeptidyl peptidase-4XanthineChemistryIn vitroIC50PharmacologyCombinatorial chemistryTriazoleEnzymeBiochemistryType 2 diabetesDiabetes mellitusMedicineEndocrinologyOrganic chemistryPeptidase Inhibition and AnalysisDiabetes Treatment and ManagementClick Chemistry and Applications