SEOM—GECOD clinical guideline for unknown primary cancer (2021)
Ferrán Losa, Isaura Fernández, Olatz Etxániz, Alejandra Giménez, Paula Gomila, L. Iglesias, Federico Longo, Esteban Nogales, Antonio Sánchez, G. Soler
Abstract
Cancer of unknown primary site (CUP) is defined as a heterogeneous group of tumors that appear as metastases, and of which standard diagnostic work-up fails to identify the origin. It is considered a separate entity with a specific biology, and nowadays molecular characteristics and the determination of actionable mutations may be important in a significant group of patients. In this guide, we summarize the diagnostic, therapeutic, and possible new developments in molecular medicine that may help us in the management of this unique disease entity.
Topics & Concepts
MedicineGuidelineDiseaseDisease entityCancerIntensive care medicineInternal medicinePathologyCancer Diagnosis and TreatmentOral and Maxillofacial PathologyTumors and Oncological Cases