In Vitro and In Vivo Electrochemical Measurement of Reactive Oxygen Species After Treatment with Anticancer Drugs
Alexander N. Vaneev, Petr V. Gorelkin, Anastasiia S. Garanina, Helena Lopatukhina, Stepan Vodopyanov, Anna V. Alova, O. O. Ryabaya, Roman Akasov, Yanjun Zhang, Pavel Novák, S. V. Salikhov, Maxim A. Abakumov, Yasufumi Takahashi, Christopher R.W. Edwards, Natalia L. Klyachko, Alexander G. Majouga, Yuri E. Korchev, Alexander S. Erofeev
Abstract
inside the tumor at different depths in response to doxorubicin. This work provides an effective new approach for the measurement of intracellular ROS by platinized nanoelectrodes.
Topics & Concepts
Reactive oxygen speciesChemistryIn vivoIntracellularDoxorubicinIn vitroAnticancer drugPharmacologyDrugBiophysicsChemotherapyBiochemistryBiologyGeneticsBiotechnologyElectrochemical sensors and biosensorsAnalytical Chemistry and SensorsElectrochemical Analysis and Applications