Novel Variant and Known Mutation in 23S rRNA Gene of <i>Mycoplasma pneumoniae</i>, Northern Vietnam, 2023
Dinh Dung Nguyen, Nhan Thi Ho, Lynn G. Dover, Anh Hang Mai Vo, Ha Thi Thanh Ly, Phuong Mai Doan, Hang Thi Nguyen, Nguyen Thi Thao Luu, An Nhat Pham, Huyen Thi Thanh Tran
Abstract
During a 2023 outbreak of Mycoplasma pneumoniae-associated community-acquired pneumonia among children in northern Vietnam, we analyzed M. pneumoniae isolated from nasopharyngeal samples. In almost half (6 of 13) of samples tested, we found known A2063G mutations (macrolide resistance) and a novel C2353T variant on the 23S rRNA gene.
Topics & Concepts
23S ribosomal RNAMycoplasma pneumoniaeMicrobiologyBiologyGene16S ribosomal RNARibosomal RNAOutbreakVirologyPneumoniaGeneticsMedicineRNAInternal medicineRibosomePneumonia and Respiratory InfectionsMicrobial infections and disease researchRespiratory viral infections research