Large-Scale Discovery of Microbial Fibrillar Adhesins and Identification of Novel Members of Adhesive Domain Families
Vivian Monzon, Alex Bateman
Abstract
Reference Proteomes database. This method allowed us to detect a high number of novel fibrillar adhesins and also novel members of adhesive domain families. To confirm our predictions of these potential adhesin protein domains, we predicted their structure using the AlphaFold tool.
Topics & Concepts
Bacterial adhesinBiologyProteomeActinobacteriaMicrobiologyFirmicutesBacteriaComputational biologyGeneGeneticsEscherichia coli16S ribosomal RNABiochemical and Structural CharacterizationRNA and protein synthesis mechanismsStreptococcal Infections and Treatments