Structural insights into ligand recognition and activation of the melanocortin-4 receptor
Huibing Zhang, Li-Nan Chen, Dehua Yang, Chunyou Mao, Qingya Shen, Wenbo Feng, Dandan Shen, Antao Dai, Shanshan Xie, Yan Zhou, Jiao Qin, Jin‐Peng Sun, Daniel H. Scharf, Tingjun Hou, Tianhua Zhou, Ming‐Wei Wang, Yan Zhang
Topics & Concepts
Melanocortin 4 receptorBiologyHeterotrimeric G proteinMelanocortin 3 receptorAgonistReceptorFunctional selectivityMelanocortinG protein-coupled receptorMelanocortin receptorLigand (biochemistry)Cell biologyG proteinBiochemistryReceptor Mechanisms and SignalingBiochemical Analysis and Sensing TechniquesRegulation of Appetite and Obesity