Litcius/Paper detail

Hypertensive Heart Disease—The Imaging Perspective

Tevfik F. Ismail, Simon Frey, Beat A. Kaufmann, David Winkel, Daniel T. Boll, Michael J. Zellweger, Philip Haaf

2023Journal of Clinical Medicine18 citationsDOIOpen Access PDF

Abstract

Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural changes include hypertrophy and interstitial fibrosis that in turn lead to functional changes including diastolic dysfunction and impaired left atrial and LV mechanical function. Ultimately, these changes can lead to heart failure with a preserved (HFpEF) or reduced (HFrEF) ejection fraction. This review will outline the clinical evaluation of a patient with hypertension and/or suspected HHD, with a particular emphasis on the role and recent advances of multimodality imaging in both diagnosis and differential diagnosis.

Topics & Concepts

MedicineCardiologyHypertensive heart diseaseVentricleInternal medicineHeart failureEjection fractionDiastoleHeart failure with preserved ejection fractionLeft ventricular hypertrophyFibrosisMuscle hypertrophyBlood pressureCardiac Imaging and DiagnosticsCardiovascular Function and Risk FactorsAdvanced MRI Techniques and Applications