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Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis

Nicholas A. Vitanza, Adam Johnson, Ashley Wilson, Christopher Brown, Jason K. Yokoyama, Annette Künkele, Cindy A. Chang, Stephanie Rawlings-Rhea, Wenjun Huang, Kristy Seidel, Catherine M. Albert, Navin Pinto, Juliane Gust, Laura S. Finn, Jeffrey G. Ojemann, Jason N. Wright, Rimas J. Orentas, Michael Baldwin, Rebecca Gardner, Michael C. Jensen, Julie R. Park

2021Nature Medicine305 citationsDOI

Topics & Concepts

MedicineTolerabilityChimeric antigen receptorDosingMedulloblastomaImmune systemOncologyInterim analysisToxicityClinical trialInternal medicineImmunotherapyAdverse effectImmunologyPathologyCAR-T cell therapy researchNanowire Synthesis and ApplicationsAdvancements in Semiconductor Devices and Circuit Design
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis | Litcius