Recent progress in covalent warheads for in vivo targeting of endogenous proteins
Naoya Shindo, Akio Ojida
Topics & Concepts
Covalent bondChemistryCysteineWarheadIn vivoChemoselectivityDrug discoveryCombinatorial chemistryBiochemistryEnzymeBiologyOrganic chemistryBiotechnologyCatalysisEngineeringAerospace engineeringClick Chemistry and ApplicationsPeptidase Inhibition and AnalysisProtein Degradation and Inhibitors