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An African perspective on genetically diverse human induced pluripotent stem cell lines

Tracey Hurrell, Jerolen Naidoo, Tiro Ntlhafu, Janine Scholefield

2024Nature Communications16 citationsDOIOpen Access PDF

Abstract

Human induced pluripotent stem cell-derived models are a well-established preclinical tool, with the ability to retain the genetics of the individual from which they are derived. Here we comment on the global representation and accessibility of such cellular tools from African population groups.

Topics & Concepts

Induced pluripotent stem cellPerspective (graphical)Stem cellBiologyGenetically modified organismGenetically engineeredComputational biologyHuman cellHuman Induced Pluripotent Stem CellsCell biologyEmbryonic stem cellCell cultureGeneticsGeneComputer scienceArtificial intelligenceCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchBiotechnology and Related Fields