Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture
Burak Gulen, Marie Rosselin, Joel Fauser, Michael F. Albers, Christian Pett, Christoph Krisp, Vivian Pogenberg, Hartmut Schlüter, Christian Hedberg, Aymelt Itzen
Topics & Concepts
ChemistryCovalent bondEnzymeNucleotideBiochemistryTernary complexSubstrate (aquarium)Combinatorial chemistryEffectorProteomeComputational biologyBiologyOrganic chemistryGeneEcologyBiochemical and Molecular ResearchCarbohydrate Chemistry and SynthesisPneumocystis jirovecii pneumonia detection and treatment