The quantity of ligand–receptor interactions between nanoparticles and target cells
Kathrin Schorr, Sebastian Beck, Oliver Zimmer, Felix Baumann, Max Keller, Ralph Witzgall, Achim Goepferich
Abstract
are involved in specific receptor binding. This corresponds to an average number of 251 binding ligands per nanoparticle, a number that can be rationalized within the biological context of the model system.
Topics & Concepts
Ligand (biochemistry)ReceptorNanoparticleChemistryBiophysicsComputational biologyCell biologyNanotechnologyBiologyMaterials scienceBiochemistryNanoparticle-Based Drug DeliveryGold and Silver Nanoparticles Synthesis and ApplicationsNanoparticles: synthesis and applications