LncRNA MEG3 targeting miR-424-5p via MAPK signaling pathway mediates neuronal apoptosis in ischemic stroke
Yanxiao Xiang, Yayun Zhang, Yanni Xia, Hua Zhao, Anchang Liu, Yuguo Chen
Abstract
and the activated MAPK pathway. These results might provide useful information for exploring the potential therapeutic targets in IS.
Topics & Concepts
MEG3Gene knockdownMAPK/ERK pathwayApoptosisDownregulation and upregulationSignal transductionLong non-coding RNACompeting endogenous RNABiologyCancer researchCell biologyBiochemistryGeneCancer-related molecular mechanisms researchCircular RNAs in diseasesMicroRNA in disease regulation