Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein
Ching‐Chi Chiu, Yi-Hsin Weng, Tu‐Hsueh Yeh, Juu‐Chin Lu, Wan-Shia Chen, Allen Han-Ren Li, Ying-Ling Chen, Kuo‐Chen Wei, Hung‐Li Wang
Topics & Concepts
Unfolded protein responseDopaminergicNeuroprotectionAutophagyBiologyCell biologyMitochondrionOxidative stressEndoplasmic reticulumEndocrinologyApoptosisDopaminePharmacologyBiochemistryParkinson's Disease Mechanisms and TreatmentsEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy