TGF-β-induced CD4+ FoxP3+ regulatory T cell-derived extracellular vesicles modulate Notch1 signaling through miR-449a and prevent collagen-induced arthritis in a murine model
Jingrong Chen, Feng Huang, Yuluan Hou, Xiaorong Lin, Rongzhen Liang, Xiaojiang Hu, Jun Zhao, Julie Wang, Nancy J. Olsen, Song Guo Zheng
Topics & Concepts
FOXP3Gene knockdownAutoimmunityImmunologyIn vivoArthritisCell biologyAdoptive cell transferTransforming growth factor betaIn vitroBiologyCancer researchT cellTransforming growth factorMedicineImmune systemCell cultureGeneticsBiochemistryBiotechnologyExtracellular vesicles in diseaseSystemic Lupus Erythematosus ResearchT-cell and B-cell Immunology