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Targeting Epidermal Growth Factor Receptor for Cancer Treatment: Abolishing Both Kinase-Dependent and Kinase-Independent Functions of the Receptor

Yuesheng Zhang

2023Pharmacological Reviews59 citationsDOIOpen Access PDF

Topics & Concepts

Cancer researchTyrosine kinaseReceptor tyrosine kinaseEpidermal growth factor receptorROR1EGFR inhibitorsErlotinibGrowth factor receptorCyclin-dependent kinase 8GefitinibKinaseBiologyPharmacologyCancerPlatelet-derived growth factor receptorMedicineSignal transductionReceptorCell biologyInternal medicineBiochemistryGrowth factorNotch signaling pathwayHER2/EGFR in Cancer ResearchLung Cancer Treatments and MutationsColorectal Cancer Treatments and Studies
Targeting Epidermal Growth Factor Receptor for Cancer Treatment: Abolishing Both Kinase-Dependent and Kinase-Independent Functions of the Receptor | Litcius