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Microbiome Clusters Disclose Physiologic Variances in Dairy Cows Challenged by Calving and Lipopolysaccharides

Johanna Tröscher-Mußotter, Johan S. Sáenz, Sandra Grindler, Jennifer Meyer, Susanne Ursula Kononov, Beate Mezger, Daniel Borda-Molina, Jana Frahm, Sven Dänicke, Amélia Camarinha‐Silva, Korinna Huber, Jana Seifert

2021mSystems21 citationsDOIOpen Access PDF

Abstract

The health of dairy cows has to be carefully considered for sustainable and efficient animal production. The microbiome of animals plays an important role in the host's nutrient supply and regulation of immune functions. We show that a certain composition of the fecal microbiome, called microbiome clusters, can be linked to an animal's health at challenging life events such as calving and inflammation. Cows with a specific set of bacteria have coped better under these stressors than have others. This novel information has great potential for implementing microbiome clusters as a trait for sustainable breeding strategies.

Topics & Concepts

MicrobiomeMetabolomeBiologyIce calvingBifidobacteriumFusobacteriaMetagenomicsDairy cattleFecesAnimal scienceMetabolomicsBacteriaMicrobiologyLactobacillusLactationBioinformaticsGeneticsPregnancy16S ribosomal RNAGeneBacteroidetesGut microbiota and healthRuminant Nutrition and Digestive PhysiologyClostridium difficile and Clostridium perfringens research
Microbiome Clusters Disclose Physiologic Variances in Dairy Cows Challenged by Calving and Lipopolysaccharides | Litcius