Electrophilic intermolecular halo-phosphorothiolation and phosphorothiolation–dearomatization of alkenes/alkynes with <i>N</i> -phosphorothiosuccinimide
Yuan Zhang, Mingyang Chen, Xu Chen, Xuesi Zhou, Yujun Fu, Xiang Liu, Hua Cao
Abstract
Herein, we developed the electrophilic intermolecular halo-phosphorothiolation of unactivated alkenes with TMSX as an activator and a nucleophilic halogen source.
Topics & Concepts
ChemistryIntermolecular forceElectrophileHaloMedicinal chemistryOrganic chemistryCombinatorial chemistryCatalysisMoleculeGalaxyPhysicsQuantum mechanicsSulfur-Based Synthesis TechniquesSynthesis and Reactivity of Sulfur-Containing CompoundsCatalytic C–H Functionalization Methods