Identification, Structure–Activity Relationships of Marine-Derived Indolocarbazoles, and a Dual PKCθ/δ Inhibitor with Potent Antipancreatic Cancer Efficacy
Jinhui Wang, Weiyang Jin, Xiaoxin Zhou, Jiaqi Li, Cheng-Dong Xu, Zhongjun Ma, Jianan Wang, Le-Le Qin, Biao Zhou, Wanjing Ding, Tingting Gao, Hangping Yao, Zhe Chen
Abstract
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Topics & Concepts
Protein kinase CChemistryStaurosporineApoptosisKinaseThreonineSerineCell growthCancer researchCancerPharmacologyBiochemistryPhosphorylationBiologyInternal medicineMedicineMicrobial Natural Products and BiosynthesisCancer Mechanisms and TherapyMicrobial Metabolism and Applications