Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core
Calina Glynn, M.R. Sawaya, P. Ge, Marcus Gallagher-Jones, Connor Short, Ronquiajah Bowman, Marcin I. Apostol, Z. Hong Zhou, David Eisenberg, José A. Rodríguez
Topics & Concepts
FibrilPrion proteinChemistryProteaseBiophysicsProtein structureProtein foldingPeptide sequenceBiochemistryBiologyEnzymeGeneDiseasePathologyMedicinePrion Diseases and Protein MisfoldingNeurological diseases and metabolismPorphyrin Metabolism and Disorders