The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1
Christopher J. Lupton, Charles Bayly-Jones, Laura D’Andrea, Cheng Huang, Ralf B. Schittenhelm, Hariprasad Venugopal, James C. Whisstock, Michelle L. Halls, Andrew M. Ellisdon
Topics & Concepts
Neurofibromin 1DimerNeurofibromatosisBiophysicsChemistryCrystallographyBiologyGeneticsOrganic chemistryNeuroblastoma Research and TreatmentsNeurofibromatosis and Schwannoma CasesAdvanced Electron Microscopy Techniques and Applications