Litcius/Paper detail

Discovery of dioxo-benzo[b]thiophene derivatives as potent YAP-TEAD interaction inhibitors for treating breast cancer

Youngchai Son, Jaeyeal Kim, Yong‐Chan Kim, Sung-Gil Chi, Tackhoon Kim, Jinha Yu

2022Bioorganic Chemistry17 citationsDOI

Topics & Concepts

ChemistryDocking (animal)CTGFTranscription factorTransactivationActivator (genetics)Reporter geneCancer researchSmall moleculeStereochemistryBiochemistryGene expressionGeneGrowth factorReceptorBiologyMedicineNursingHippo pathway signaling and YAP/TAZ