Mitochondrial redox-driven mitofusin 2 S-glutathionylation promotes neuronal necroptosis via disrupting ER-mitochondria crosstalk in cadmium-induced neurotoxicity
Lin Che, Chuanli Yang, Yu Chen, Zili Wu, Ze‐Bang Du, Jia‐Shen Wu, Cong-Ling Gan, Siping Yan, Jing Huang, Nijun Guo, Yu‐Chun Lin, Zhong‐Ning Lin
Topics & Concepts
MFN2MitochondrionNecroptosisCell biologyMitochondrial ROSVoltage-dependent anion channelNeurotoxicityCrosstalkChemistryReactive oxygen speciesMitochondrial permeability transition poreBiologymitochondrial fusionProgrammed cell deathBiochemistryApoptosisBacterial outer membraneToxicityOrganic chemistryGeneEscherichia coliPhysicsMitochondrial DNAOpticsTrace Elements in HealthMitochondrial Function and PathologyHeavy Metal Exposure and Toxicity