Early age of onset and broad cancer spectrum persist in MSH6- and PMS2-associated Lynch syndrome
Ying L. Liu, Karen A. Cadoo, Anna Maio, Zalak Patel, Yelena Kemel, Erin Salo‐Mullen, Amanda Catchings, Megha Ranganathan, Sarah Kane, Robert A. Soslow, Ozge Ceyhan‐Birsoy, Diana Mandelker, Maria I. Carlo, Michael F. Walsh, Jinru Shia, Arnold J. Markowitz, Kenneth Offit, Zsofia K. Stadler, Alicia Latham
Topics & Concepts
MSH6Lynch syndromeMicrosatellite instabilityPMS2MedicineCancerInternal medicineOncologyMLH1Prostate cancerColorectal cancerBiologyDNA mismatch repairGeneticsAlleleGeneMicrosatelliteGenetic factors in colorectal cancerMultiple and Secondary Primary CancersGenomics and Rare Diseases