Exploring the molecular basis of tucatinib interaction with human serum albumin: A spectroscopic and computational analysis
Mohd Amir, Faisal Nabi, Sayyed Mohd Fuzail Zaheer, Rizwan Hasan Khan, Saleem Javed
Topics & Concepts
Human serum albuminChemistryCircular dichroismHydrogen bondMolecular dynamicsProtein secondary structureBinding constantCrystallographyvan der Waals forceHydrophobic effectStereochemistryBinding siteComputational chemistryBiochemistryMoleculeOrganic chemistryProtein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsAnalytical Chemistry and Chromatography