IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death
Choong-Sil Lee, Gyuho Hwang, Young Woo Nam, Chi Hyun Hwang, Jaewhan Song
Topics & Concepts
RIPK1NecroptosisProgrammed cell deathTumor necrosis factor alphaCell biologyFADDApoptosisIκB kinaseChemistrySignal transductionBiologyCancer researchNF-κBCaspaseImmunologyBiochemistryCell death mechanisms and regulationNF-κB Signaling Pathwaysinterferon and immune responses