Litcius/Paper detail

Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV Test

Heba H. Mostafa, Karen C. Carroll, Rachel Hicken, Gregory J. Berry, Ryhana Manji, Elizabeth Smith, Jennifer L. Rakeman, Randal C. Fowler, Mindy Leelawong, Susan M. Butler‐Wu, David Quintero, Minette Umali-Wilcox, Robert Kwiatkowski, David H. Persing, Fred Weir, Michael J. Loeffelholz

2020Journal of Clinical Microbiology93 citationsDOIOpen Access PDF

Abstract

= 153). Standard-of-care tests to which the Cepheid panel was compared included the Cepheid Xpert Xpress SARS-CoV-2, Cepheid Xpert Xpress Flu/RSV, GenMark ePlex respiratory panel, BioFire respiratory panel 2.1 and v1.7, DiaSorin Simplexa COVID-19 Direct, and Hologic Panther Fusion SARS-CoV-2 assays. The Xpert Xpress SARS-CoV-2/Flu/RSV test showed high sensitivity and accuracy for all analytes included in the test. This test will provide a valuable clinical diagnostic and public health solution for detecting and differentiating SARS-CoV-2, influenza A and B virus, and RSV infections during the current respiratory virus season.

Topics & Concepts

GeneXpert MTB/RIFVirologyMedicineOrthomyxoviridaeDiagnostic testPublic healthSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirusRapid diagnostic testInfluenza A virusCoronavirus disease 2019 (COVID-19)SputumInfectious disease (medical specialty)Veterinary medicineTuberculosisInternal medicinePathologyDiseaseRespiratory viral infections researchSARS-CoV-2 detection and testingViral gastroenteritis research and epidemiology