Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli
Hidetada Hirakawa, Kazutomo Suzue, Ayako Takita, Wataru Kamitani, Haruyoshi Tomita
Abstract
mutant did not further decrease bacterial internalization. These combined results suggest that OmpX contributes to flagellar production in UPEC and then sustains UPEC virulence associated with bacterial internalization and aggregation within urinary tract cells and colonization in the urinary tract.
Topics & Concepts
VirulenceBiologyBacterial outer membraneEscherichia coliMicrobiologyEscherichia coli ProteinsEnterobacteriaceaeMembrane proteinBacterial proteinVirulence factorBacteriaFlagellumMembraneBiochemistryGeneGeneticsEscherichia coli research studiesAntibiotic Resistance in BacteriaBacterial Genetics and Biotechnology