Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of <i>Neisseria gonorrhoeae</i>
Nader S. Abutaleb, Ahmed E. M. Elhassanny, Alessio Nocentini, Chad S. Hewitt, Ahmed Elkashif, Bruce R. Cooper, Claudiu T. Supuran, Mohamed N. Seleem, Daniel P. Flaherty
Abstract
agents.
Topics & Concepts
AcetazolamideNeisseria gonorrhoeaeChemistryCarbonic anhydrasePotencyPharmacologyMicrobiologyEnzymeInternal medicineIn vitroBiochemistryMedicineBiologyEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities