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PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treatment by regulating the PI3K/Akt1 pathway

Ju Zhou, Saber İmani, Marzieh Dehghan Shasaltaneh, Shuguang Liu, Tao Lü, Junjiang Fu

2021Molecular Biology Reports23 citationsDOI

Topics & Concepts

ThymoquinoneAKT1Cancer researchBreast cancerPI3K/AKT/mTOR pathwayBiologyGeneticsMedicineOncologyInternal medicineComputational biologyBioinformaticsCancerSignal transductionBiochemistryAntioxidantNigella sativa pharmacological applicationsChemotherapy-induced organ toxicity mitigationHedgehog Signaling Pathway Studies
PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treatment by regulating the PI3K/Akt1 pathway | Litcius