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ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β

Yuna Jia, Xiaoyong Huang, Haiyan Shi, Mingming Wang, Jie Chen, Huahua Zhang, Danyang Hou, Hongmei Jing, Juan Du, Huihui Han, Jing Zhang, Jing Zhang

2023Experimental Cell Research13 citationsDOI

Topics & Concepts

Wnt signaling pathwayEpithelial–mesenchymal transitionGene knockdownCancer researchBiologyCateninMetastasisSignal transductionDownregulation and upregulationVimentinBeta-cateninCell growthCell adhesionCell migrationCell biologyCancerApoptosisCellImmunologyImmunohistochemistryBiochemistryGeneticsGeneCell Adhesion Molecules ResearchPeptidase Inhibition and AnalysisWnt/β-catenin signaling in development and cancer
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β | Litcius