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Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior

Seungjoon Kim, Dongseok Park, Jinhu Kim, Dong‐Wook Kim, Hyeonho Kim, Takuma Mori, Hyeji Jung, Dongsu Lee, Sookyung Hong, Jongcheol Jeon, Katsuhiko Tabuchi, Eunji Cheong, Jaehoon Kim, Ji Won Um, Jaewon Ko

2021Cell Reports23 citationsDOIOpen Access PDF

Abstract

interneurons, to orchestrate excitation-to-inhibition balance and control anxiety-like behavior.

Topics & Concepts

GABAergicNeuroscienceGephyrinInterneuronNeurotransmissionBiologyHippocampal formationSynapseGuanine nucleotide exchange factorCell biologyInhibitory postsynaptic potentialSignal transductionReceptorGlycine receptorBiochemistryAmino acidGlycineNeuroscience and Neuropharmacology ResearchRetinal Development and DisordersCellular transport and secretion
Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior | Litcius