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Stem cell-derived exosomes for dentin-pulp complex regeneration: a mini-review

Dina A. Hammouda, Alaa Mansour, Mahmoud A. Saeed, Ahmed R. Zaher, Mohammed E. Grawish

2023Restorative Dentistry & Endodontics13 citationsDOIOpen Access PDF

Abstract

studies have indicated that exosomes triggered the regeneration of dentin-pulp-like tissue, and exosomes isolated under odontogenic circumstances are particularly strong inducers of tissue regeneration and stem cell differentiation. Exosomes are a promising regenerative tool for DPC in cases of small pulp exposure or for whole-pulp tissue regeneration.

Topics & Concepts

Cell biologyMicrovesiclesMesenchymal stem cellPulp (tooth)Regeneration (biology)Stem cellDental pulp stem cellsBiologyAngiogenesisImmunologyCancer researchmicroRNAMedicinePathologyBiochemistryGeneExtracellular vesicles in diseaseMesenchymal stem cell researchElectrospun Nanofibers in Biomedical Applications