Gadolinium-Based Contrast Agents: Updates and Answers to Typical Questions Regarding Gadolinium Use
Benjamin Cheong, James M. Wilson, Ourania Preventza, Raja Muthupillai
Abstract
Gadolinium-based contrast agents have expanded the diagnostic usefulness and capability of magnetic resonance imaging. Despite their highly favorable safety profile, these agents have been associated with nephrogenic systemic fibrosis in a small number of patients who have advanced kidney disease. Recently, trace amounts of gadolinium deposition in the brain and other organs have been reported after contrast exposure, even in patients with normal renal function. In this review, we provide a brief overview of recent updates and discuss typical clinical situations related to the use of gadolinium-based contrast agents.
Topics & Concepts
Nephrogenic systemic fibrosisGadoliniumMedicineContrast (vision)Magnetic resonance imagingRadiologyComputer scienceArtificial intelligenceMetallurgyMaterials scienceLanthanide and Transition Metal ComplexesAdvanced MRI Techniques and ApplicationsMRI in cancer diagnosis