<i>In-silico</i> screening of plant-derived antivirals against main protease, 3CL<sup>pro</sup> and endoribonuclease, NSP15 proteins of SARS-CoV-2
Aniket Sharma, Shubham Goyal, Arvind Kumar Yadav, Pawan Kumar, Lovely Gupta
Abstract
and pre-clinical experiments would validate the potential inhibitors of SARS-CoV-2 proteins.
Topics & Concepts
ADMEEndoribonucleaseIn silicoDocking (animal)Drug discoveryNelfinavirPharmacologyChemistryProteasePharmacophoreBiologyDrugComputational biologyBiochemistryVirologyVirusEnzymeMedicineGeneAntiretroviral therapyRNANursingViral loadRNase PSARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery MethodsTransgenic Plants and Applications