Heat inactivation of monkeypox virus
Christophe Batéjat, Quentin Grassin, Maxence Feher, Damien Hoinard, Jessica Vanhomwegen, Jean‐Claude Manuguerra, India Leclercq
Abstract
Different kinds of media spiked with monkeypox virus (MPXV) were subjected to heat inactivation at different temperatures for various periods of time. The results showed that MPXV was inactivated in less than 5 min at 70 °C and less than 15 min at 60 °C, with no difference between viruses from the West African and Central African clades. The present findings could help laboratory workers to manipulate MPXV in optimal biosafety conditions and improve their protocols.
Topics & Concepts
MonkeypoxVirus inactivationBiosafetyVirologyVirusBiologyGeneEcologyGeneticsRecombinant DNAVacciniaPoxvirus research and outbreaksBacillus and Francisella bacterial researchBacteriophages and microbial interactions