The Facts and Family Secrets of Plasmids That Replicate via the Rolling-Circle Mechanism
M. Pilar Garcillán-Barcia, Radoslaw Pluta, Fabián Lorenzo-Díaz, Alicia Bravo, Manuel Espinosa
Abstract
family represented by plasmid pMV158, which has been revisited and updated. Family secrets, like a putative open reading frame of unknown function, are reported. We conclude that basic research on RCR plasmids is of importance, and our perspectives contemplate the concept of One Earth because we should incorporate bacteria into our daily life by diminishing their virulence and, at the same time, respecting their genetic diversity.
Topics & Concepts
PlasmidBiologyGeneticsGeneHorizontal gene transferDNAOrigin of replicationT-DNA Binary systemENCODEBacterial conjugationVirulenceDNA replicationBacteriaOpen reading frameMechanism (biology)RepliconReplication (statistics)Mobile genetic elementsBacterial geneticsGenomeComputational biologyAutonomously replicating sequenceHost (biology)Bacterial Genetics and BiotechnologyAntibiotic Resistance in BacteriaOrigins and Evolution of Life