Metal-Free <i>ortho</i> C–H Borylation of Thiobenzamides
Jianxing Lv, Yixuan Liang, Y. OUYANG, Hua Zhang
Abstract
A BBr 3 -mediated S-directed ortho C–H borylation of thiobenzamides was developed. A variety of ortho -borylated thiobenzamides were obtained in moderate to good yields with a wide functional group tolerance under simple and metal-free conditions. This transformation provided a convenient and practical route to important functionalized thiobenzamides.
Topics & Concepts
BorylationChemistryFunctional groupCombinatorial chemistryMetalTransformation (genetics)Simple (philosophy)Medicinal chemistryStereochemistryOrganic chemistryBiochemistryArylAlkylPolymerEpistemologyPhilosophyGeneCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesSynthesis and Catalytic Reactions