Litcius/Paper detail

Fluorescence, ultrasonic and photoacoustic imaging for analysis and diagnosis of diseases

Binbin Chu, Zhiming Chen, Haoliang Shi, Xiaofeng Wu, Houyu Wang, Fenglin Dong, Yao He

2023Chemical Communications50 citationsDOIOpen Access PDF

Abstract

imaging applications. Taking advantage of the excellect penetration depth of acoustic signals, ultrasonic imaging has been widely applied for determining the location, size and shape of organs, identifying normal and abnormal tissues, as well as confirming the edges of lesions in hospitals. Thus, in the second section, we will briefly summarize recent advances in ultrasonic imaging techniques for diagnosing diseases in deep tissues. Nevertheless, the absence of lesion targeting and dependency on a professional technician may lead to the possibility of false-positive diagnosis. By combining the merits of both optical and acoustic signals, newly-developed photoacoustic imaging, simultaneously featuring higher temporal and spatial resolution with good sensitivity, as well as deeper penetration depth, is discussed in the third secretion. In the final part, we further discuss the major challenges and prospects for developing imaging technology for accurate disease diagnosis. We believe that these non-invasive imaging technologies will introduce a new perspective for the precise diagnosis of various diseases in the future.

Topics & Concepts

Photoacoustic imaging in biomedicineFluorescenceUltrasonic sensorUltrasoundFluorescence-lifetime imaging microscopyMaterials scienceBiomedical engineeringMedicineRadiologyOpticsPhysicsPhotoacoustic and Ultrasonic ImagingNanoplatforms for cancer theranosticsOptical Imaging and Spectroscopy Techniques