Galactose oxidase oxidation and glycosidase digestion for glycoRNA analysis
Jianbo Deng, Xinyu Miao, Xiaotong Wang, S. M. Wen, Zeyang Zhou, Shuwei Li, Junhong Jiang, Xiaodong Yang, Shuang Yang
Abstract
Solid-phase glycoRNA enrichment provides a universal approach for capturing glycosylated RNAs, enabling the identification of glycoRNAs and facilitating functional studies.
Topics & Concepts
GalactoseGalactose oxidaseChemistryGlycoside hydrolaseDigestion (alchemy)BiochemistryEnzymeChromatographyRNA Interference and Gene DeliveryRNA and protein synthesis mechanismsRNA regulation and disease