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SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis

Jiaqi Shi, Li Chen, Xu Wang, Xin Ma

2025Inflammation Research13 citationsDOI

Topics & Concepts

Endoplasmic reticulumCell biologyOsteoarthritisChemistrySignal transductionUnfolded protein responseMedicineBiologyPathologyAlternative medicineFerroptosis and cancer prognosisInflammasome and immune disordersCancer-related molecular mechanisms research
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis | Litcius